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The poor prognosis and high susceptibility to recurrence in patients with tumors such as HGSOC can be attributed to the genetic instability of these tumors
As a key antioxidant transcription factor, NRF2 activity decreases during heart failure, while miRNAs modulate NRF2 and its associated antioxidant proteins through EV, thereby regulating oxidative stress [166]
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Low-dose metronomic cyclophosphamide combined with vascular disrupting therapy induces potent antitumor activity in preclinical human tumor xenograft models
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